Purigen Biosystems, Inc.

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Purigen Literature


    PDF 3.15 MB
    01: IONIC® Purification System
    Nucleic Acid Purification – Pure and Simple: A new DNA and RNA extraction and purification system from Purigen Biosystems.
    PDF 5.65 MB
    01: Solving the problem of rare: automated microfluidics for accurate variant detection by PCR-free WGS of very small human samples
    In collaboration with UCSF and Miroculus @ AGBT 2021
    PDF 5.53 MB
    02: Using Isotachophoresis as a Novel Method to Improve the Yield and Quality of Nucleic Acid Purification from FFPE Samples
    Improve the Yield and Quality of Nucleic Acid Purification from FFPE Samples - presented @ ABRF 2020
    PDF 4.55 MB
    02a: Isotachophoresis Improves Nucleic Acid Extraction and Purification from FFPE Samples
    With a simplified workflow and separation based solely on the electrophoretic mobility of the molecules in a sample, Purigen’s Ionic Purification System offers an alternative for FFPE sample purification for NGS that has less risk of further damage to nucleic acids or bias toward specific fragment length or GC content.
    PDF 521.01 KB
    02b: Increased DNA Yield and Reduced PCR Duplicates Using the Ionic System
    FFPE tissue samples are known to produce low yields of nucleic acid that is often of a lower quality by comparison to nucleic acid from fresh frozen tissue, particularly samples that have been stored for several years or longer. When FFPE tissue is limited, conventional extraction and purification technologies may not produce enough high quality DNA to meet the recommended library preparation input requirements for next-generation sequencing (NGS).
    PDF 124.24 KB
    03: Proof-of-Performance Study Info/Form
    See the Purigen Advantage: Send us your samples and see the difference.
    PDF 2.02 MB
    04: Purigen FFPE Workflow
    Simplified FFPE Workflow: < 3 minutes of hands-on time per sample
    PDF 518.00 KB
    06: Get what you need from your FFPE samples
    Finally, get what you need from your FFPE samples