Purigen Biosystems, Inc.

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  • No beads, columns, or surface-binding

    Simple Charge-based DNA Extraction

    Isotachophoresis separates and concentrates charged molecules in solution solely based on their electrophoretic mobility for pure DNA extraction.

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  • Proof-of-Performance (POP) Study

    See the Purigen Ionic Advantage

    We invite you try Purigen and see the difference. Our POP program is available to any researcher wanting to compare their traditional methods / results to the Ionic Purification System.

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  • White Paper

    Isotachophoresis Improves
    Nucleic Acid Extraction for FFPE

    Download our new white paper and learn how the Ionic system is transforming FFPE sample analysis.

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  • Purigen Biosystems

    Nucleic Acid Purification – Pure and Simple™

    The Ionic® Purification System isolates pure, native nucleic acid without the use of harsh lysis steps or chaotropic salts.

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  • Purigen Ionic Kits

    Simplify Your Purification Workflows

    Purigen protocols, fluidic chips, and reagents maximize nucleic acid yield and quality with fewer manual steps.

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  APP NOTE   -   Increased DNA Yield from FFPE Samples Purified Using the Ionic® System Reduces PCR Duplicates in NGS   -   DOWNLOAD PDF    
Pure, Native Nucleic Acid
Biological samples are gently lysed without the use of chaotropic salts. Nucleic acids are not dehydrated or denatured.
Higher Amplifiable Yields
Extract up to 50% more DNA from cultured cells and 3.5x or more from FFPE tissue samples versus traditional column-based methods.
No Beads, Columns, or Surface-binding
Nucleic acids are purified solely based on electrophoretic mobility. Elimination of binding, washing, and stripping reduces sample loss and contamination.
No Risk Downstream
Purification is not biased toward nucleic acids of a certain length or GC content.
Superior Workflow for FFPE
Purification of nucleic acids from FFPE scrolls or slides requires less than 3 minutes of hands-on time per sample (lysis included). No chemical deparaffinization is required.
Automated Nucleic Acid Purification
Nucleic acids are automatically separated and concentrated from sample lysate on the Purigen system in 60 minutes.

See the Ionic Purification System in Action

The application of ITP to purify and quantify nucleic acids from complex biological samples was pioneered by Purigen co-founder and Stanford University Professor, Juan G. Santiago. The Ionic Purification System is compatible with a range of samples including cells and FFPE to help researchers, scientists, pathologists, and oncologists find the best method for DNA and RNA extraction.

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PURIGEN FFPE Automated Workflow

Total hands-on time is ~24 minutes per 8 samples

Purigen FFPE Workflow
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