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Purigen Literature

Literature

  • POSTER
    PDF 5.65 MB
    00: Solving the problem of rare: automated microfluidics for accurate variant detection by PCR-free WGS of very small human samples
    In collaboration with UCSF and Miroculus @ AGBT 2021
  • BROCHURE
    PDF 3.15 MB
    01a: IONIC® Purification System
    Nucleic Acid Purification – Pure and Simple: A new DNA and RNA extraction and purification system from Purigen Biosystems.
  • BROCHURE
    PDF 1.15 MB
    01b: IONIC® FFPE Complete Purification
    Simultaneous Extraction and Purification of RNA and DNA from FFPE Samples
  • WHITE PAPER / APP NOTE
    PDF 4.55 MB
    02a: Isotachophoresis Improves Nucleic Acid Extraction and Purification from FFPE Samples
    With a simplified workflow and separation based solely on the electrophoretic mobility of the molecules in a sample, Purigen’s Ionic Purification System offers an alternative for FFPE sample purification for NGS that has less risk of further damage to nucleic acids or bias toward specific fragment length or GC content.
  • WHITE PAPER / APP NOTE
    PDF 521.01 KB
    02b: Increased DNA Yield and Reduced PCR Duplicates Using the Ionic System
    FFPE tissue samples are known to produce low yields of nucleic acid that is often of a lower quality by comparison to nucleic acid from fresh frozen tissue, particularly samples that have been stored for several years or longer. When FFPE tissue is limited, conventional extraction and purification technologies may not produce enough high quality DNA to meet the recommended library preparation input requirements for next-generation sequencing (NGS).
  • POSTER
    PDF 1.41 MB
    03a: Simultaneous, High-yield Extraction of DNA and RNA from FFPE Tissue
    Simultaneous extraction and purification of both RNA and DNA from FFPE tissue samples is critical to enable multiple downstream analyses from rare or limited samples. To avoid yield loss, most technologies use a serial isolation approach where DNA and RNA are separated after lysis by filtration or precipitation before entering separate purification workflows. This results in twice the number of purification steps per sample.
  • POSTER
    PDF 5.53 MB
    03b: Using Isotachophoresis as a Novel Method to Improve the Yield and Quality of Nucleic Acid Purification from FFPE Samples
    Improve the Yield and Quality of Nucleic Acid Purification from FFPE Samples - presented @ ABRF 2020
  • FLYER
    PDF 2.02 MB
    04: Purigen FFPE Workflow
    Simplified FFPE Workflow: < 3 minutes of hands-on time per sample
  • FLYER
    PDF 124.24 KB
    04a: Proof-of-Performance Study Info/Form
    See the Purigen Advantage: Send us your samples and see the difference.
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